Open access
Jul 2026
Crocin I delays cellular senescence potentially via modulating SIRT1/PKM2 expression to improve lactate homeostasis in vitro
Crocin I has a protective effect against D-galactose-induced aging in rat models; however, its specific mechanism on delaying cellular senescence remains unclear. The aim of the present study was to investigate the interventional effect and related molecular mechanism of Crocin Ⅰ on replicative senescence and premature...
Yicheng Fu, Zhiwei Ding, Yunchuang Chang et al.
· Experimental and Therapeutic... · 0 citations