Strigolactones and antifungals induce internalization of major facilitator superfamily transporters.
The major facilitator superfamily (MFS) is a diverse class of selective transporters that move a range of substrates across membranes. Despite their central role in cellular homeostasis, chemically perturbing MFS transporters is challenging. Here, we elucidate how the plant hormone, strigolactone (SL), internalizes the...