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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

George Wanes

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Open access Oct 2026

Molecular sterics guide tmRNA translocation on the ribosome

Translation of defective mRNA transcripts can lead to the formation of stalled “non-stop” ribosome complexes. To rescue these ribosomes, bacteria have evolved a mechanism called trans-translation that is mediated by transfer-messenger RNA (tmRNA) and small protein B (SmpB). During the translocation step of trans-transl...

George Wanes, K. Keiler, Christine M. Dunham et al. · 0 citations
Open access Aug 2026

Ribosomal protein bL27 protects translating ribosomes from tmRNA-SmpB

Trans-translation and bL27 data are linked and support a model in which the amino terminus of bL27 acts as a gatekeeper to prevent tmRNA from sterically interfering with tRNA (transfer RNA) on the ribosome.

Divyasorubini Seerpatham, George Wanes, Chathuri Pathirage et al. · 0 citations

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