Open access
Sep 2026
Prognostic Impact of Lymphovascular Invasion on Distant Metastasis in HPV-Negative Head and Neck Cancer.
BACKGROUND Lymphovascular invasion (LVI) is a recognized poor prognostic factor in head and neck squamous cell carcinoma (HNSCC), particularly for regional recurrence and overall survival. However, its role in predicting distant metastasis, especially in HPV-negative HNSCC, remains unclear. OBJECTIVE To evaluate the...
M. Khoury, Alex Mlynarek, Keith Richardson et al.
· Head and Neck · 0 citations