Open access
Aug 2026
Targeted degradation of alpha-synuclein impedes PFF-induced aggregation
The Affinity-directed PROtein Missile system is employed and targeted degradation of α-synuclein impedes the pre-formed fibril (PFF)-induced aggregation of α-synuclein in primary neurons derived from rats expressing human α-synuclein.
Bill Carton, Géraldine Gelders, Gajanan Sathe et al.
· npj Parkinson's Disease · 0 citations