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Author

Gergana Galabova

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Review Open access Oct 2026

Transcriptional cyclin-dependent kinases as therapeutic targets in bone metastasizing cancers

The potential of CDK9 inhibition in bone metastases is explored, including effects on both tumor cell survival and RANKL-NF-κB -driven osteoclastogenic bone microenvironment, and how CDK12 and CDK13 may provide complementary or context-dependent therapeutic opportunities are discussed.

T. Kähkönen, Gergana Galabova, M. Thormann et al. · 0 citations

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