G.G. Roshan Pradeep Ratupaskatiye

Dihalogenated indoles with antimicrobial activity against C. acnes and polymicrobial biofilms.

Acne vulgaris is a chronic inflammatory skin disorder in which Cutibacterium acnes contributes to disease persistence through biofilm formation, lipid metabolism, and production of inflammatory metabolites within the pilosebaceous unit. Targeting bacterial physiological pathways that sustain these processes represents...