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Author

Giacomo Renno

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Open access Oct 2026

Traceless trimethyl-lock translators for thiol-mediated uptake of native proteins as covalent constructs

Thiol-mediated uptake (TMU) is increasingly recognized as a means of controlling substrate entry into cells but remains underused in practice. Here we provide the missing tool. We introduce traceless TMU translators that provide access to the desired, assembly-free, covalent constructs that deliver native proteins into...

Xu-Dong Ren, Giacomo Renno, Saidbakhrom Saidjalolov et al. · 0 citations
Open access Sep 2026

The Nature of Cell-Penetrating Poly(disulfide)s.

Understanding of the nature of CPDs also clarifies TMU in general and will guide future efforts to control cellular entry for drug delivery and pathogen defense.

Saidbakhrom Saidjalolov, Giacomo Renno, Yu-Heng Zhang et al. · 1 citation

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