Giorgos Hiotis

The bacterial mechanosensitive channel MscM gates through concerted changes in its transmembrane and cytoplasmic domains

The mechanosensitive channel of small conductance (MscS) is the founding member of the family of MscS-like channels, which share a structurally conserved core but feature additional structural elements that define their specific channel characteristics. Here, we characterize the structure and function of the Escherichi...