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Author

Giovanni Canino

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Review Open access Oct 2026

Stress Echocardiography Beyond Wall Motion in ANOCA/INOCA: Coronary Microvascular Dysfunction and Multiparametric Assessment

Stress echocardiography has traditionally been used to identify inducible regional wall motion abnormalities caused by flow-limiting epicardial coronary artery disease. However, a substantial proportion of patients with angina or objective evidence of myocardial ischaemia have no obstructive coronary stenoses, highligh...

N. Carabetta, Pierfrancesco Durante, Assunta Di Costanzo et al. · 0 citations
Open access Jul 2026

Robust Myocardial Regeneration After Selective Cardiomyocyte Loss Is Driven by Cardiac Stem Cell Activation Through the miR-221–p57 Axis

Mechanistically, it is shown that miR-221-dependent repression of p57 governs the transition from quiescence--to activation—to differentiation—to quiescence of the CSCs, defining a reversible regulatory program which, under the proper conditions, endows the adult myocardium with robust CM regenerative competence.

E. Cianflone, F. Marino, Mariangela Scalise et al. · 0 citations

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