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Preprint Sep 2026

Optimization of Deep Learning Model for Denoising Dose Profiles in Proton Therapy

This work replaces the standard MSE training objective with a differentiable $\gamma$-index-based loss, extended to native 3D operation, and demonstrates that directly optimising the clinical evaluation metric yields a mean Gamma Passing Rate that is critical for clinical deployment.

J. Jawaid, M. Spezialetti, Gabriele Libardi et al. · 0 citations
Open access Sep 2026

On the Minimization of Graph Counterfactual Explanations: Theory and a Local Bounded Search Algorithm

Graph counterfactual explainability (GCE) addresses the interpretability limitations of opaque machine learning models on graph-structured data by producing graph counterfactuals (GCs): alternative graphs that remain maximally similar to a given instance while inducing a different model prediction. State-of-the-art GCE...

Rodrigo García, Mario Alfonso Prado-Romero, Francesco Gullo et al. · 1 citation

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