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Author

Giuseppe Esposito

2 papers indexed here

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Open access Oct 2026

Engineered probiotic-mediated palmitoylethanolamide biosynthesis protects against colitis-associated liver injury

Chronic colitis promotes secondary liver injury through disruption of the gut–liver axis, whereby intestinal barrier breakdown enables portal translocation of microbial products that activate hepatic inflammatory and fibrogenic pathways. Palmitoylethanolamide (PEA), an endogenous ALIAmide acting primarily via PPAR-α, e...

Irene Palenca, Silvia Basili Franzin, G. Sarnelli et al. · 0 citations
Open access Sep 2026

Palmitoylethanolamide as an Intestinal Gatekeeper: Linking Inflammation, Angiogenesis and Colorectal Cancer Interception

Angiogenesis is a major determinant of tumor growth, progression and metastatic potential, and its persistent activation is closely intertwined with chronic inflammation. This relationship is particularly relevant in malignancies that arise through a prolonged inflammation-to-carcinogenesis continuum, where pathologica...

Irene Palenca, G. Sarnelli, Giuseppe Esposito · 0 citations

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