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Author

Gohar Sevoyan

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Open access Jul 2026

Temporal Dynamics of PD-L1 Surface in RKO Cells: Characterizing the Reversible Impact of the Small-Molecule Dimerizer BMS-202

These findings suggest that BMS-202-induced changes in surface PD-L1 are acute and reversible, with levels returning to baseline within 24 h post-exposure, and reveal a dynamic regulatory mechanism where small-molecule-induced dimerization triggers rapid protein trafficking and transient surface depletion.

Gohar Sevoyan, Daniel Polianczyk, Siranuysh Grabska et al. · 0 citations

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