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Author

Goki Yamada

2 papers indexed here

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Sep 2026

Upamostat potentiates bortezomib cytotoxicity and delays proteasome recovery in bortezomib-resistant malignant lymphoma cells through modulation of the DDI2/NRF1 axis.

Proteasome inhibitors such as bortezomib (BTZ) are potent against hematological malignancies, but acquired resistance remains a major obstacle to durable clinical responses. DNA damage-inducible 1 homolog 2 (DDI2)-mediated processing of nuclear factor erythroid 2-related factor 1 (NRF1) contributes to adaptive proteaso...

Atsumi Ota, Sota Maruyama, Yudai Kudo et al. · 0 citations
Open access Aug 2026

Differential physiological, behavioral, and medial prefrontal cortex transcriptomic responses to chronic restraint stress between BALB/c and C57BL/6J mice

Chronic stress is a major risk factor for psychiatric disorders such as depression and anxiety, yet the biological basis of individual differences in stress susceptibility and resilience remains poorly understood. Here, we examined physiological, behavioral, and medial prefrontal cortex (mPFC) transcriptomic responses...

Taiga Kurihara, Aoi William Omi, Yuka Nakasone et al. · 0 citations

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