The Multifaceted Role of the P2X7 Receptor in Alzheimer's Disease: A Unifying Pathological Link.
The role of the Purinergic receptor (P2X7 receptor), a ligand-gated ion channel activated by extracellular ATP, was examined across existing cellular mechanisms and possible pathways involved in AD, as well as the co-pathologies encompassed and their hypothetical relationship with the P2X7 receptor.