Author

Goran Micevic

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Open access Jul 2026

Targeting DNMT1 augments anti-tumor CD8⁺ T cell function

DNMT1 targeting is established as a promising strategy to counteract CD8⁺ T cell exhaustion and potentiate ICI efficacy and enhances the effector function of melanoma patient-derived tumor infiltrating lymphocytes after prolonged ex vivo expansion.

M. Deshmukh, Danielle K. Sohai, Kamal Obbad et al. · bioRxiv · 0 citations