Author

Gregor Kasprian

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Open access Sep 2026

Fetal Brain Abnormalities in Trisomy 21 and Associated Neurodevelopmental Outcome: Key Factors to Identify Differences in Neurodevelopmental Outcome?

OBJECTIVE Trisomy 21 (T21) is associated with various neurological impairments. However, the mechanisms of fetal brain development in T21 and their impact on neurodevelopmental outcomes remain unclear, limiting prenatal counseling. Therefore, this study aims to assess neuropathological changes in fetuses with T21 and t...

C. Haberl, P. Palmrich, Eva Karner et al. · Prenatal Diagnosis · 0 citations

Open access Sep 2026

Re-evaluating impaired consciousness in temporal lobe epilepsy: The role of language dominance and network reorganization.

OBJECTIVE Temporal lobe epilepsy (TLE) frequently affects clinically-classified ictal consciousness, which the 2025 International League Against Epilepsy (ILAE) classification operationalizes through clinical assessment of awareness and responsiveness. It remains uncertain whether the spatial lateralization between the...

R. Stepponat, M. Berger, Laurin Schäfer et al. · Epilepsia · 0 citations

Open access Aug 2026

Uncovering Individual Language Vulnerability in Epilepsy Through Functional Connectivity Laterality.

BACKGROUND Language processing is organized in brain networks, generally lateralized to the left hemisphere. In clinical routine, task-based functional MRI (fMRI) is the gold standard for non-invasive evaluation of language lateralization. However, standard fMRI does not account for the individual heterogeneity of lang...

R. Stepponat, Mehmet-Salih Yildirim, M. Berger et al. · Clinical Neuroradiology · 0 citations