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Guan-Chao Xie

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Open access Oct 2026

TOP2A Overexpression as a Prognostic Biomarker in High-Grade Meningioma: An Integrated Single-Cell and Bulk Transcriptomic Study

While prior single-cell studies have identified proliferative neoplastic subpopulations, the prognostic and therapeutic implications of TOP2A focal copy-number status have not been defined. This study aimed to delineate the cellular architecture of high-grade meningioma and to evaluate the clinical and prognostic signi...

Hong-Qing Cai, Guan-Chao Xie, Hou-Jie Liu et al. · 0 citations

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