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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Guanmao Chen

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Open access Sep 2026

Inflammation is associated with altered functional connectivity of the cingulate cortex in individuals with subthreshold depression

Subthreshold depression (StD) represents a critical prodromal phase that often precedes clinical depression. Identifying biological indicators during this stage is essential for the prophylaxis of major depressive disorder. The present study investigated the interplay between serum pro-inflammatory cytokines, functiona...

Zhang-Zhang Qi, Pan Chen, Guan-Mao Chen et al. · 0 citations
Open access Aug 2026

Disrupted white matter function in subthreshold depression correlate with cognitive, neurotransmitter, and genetic profiles.

Findings reveal WM functional alterations in StD that are associated with mood and cognitive disturbances, and suggest that these alterations may be linked to underlying transcriptomic and neurotransmitter correlates.

Zi-Xuan Guo, Pan Chen, Guan-Mao Chen et al. · 0 citations
Open access Jul 2026

Associations between thyroid hormones and biochemical metabolism in major depressive disorder patients with and without comorbid eating disorders.

Findings reveal concurrent thyroid hormone irregularities and neurometabolic changes in the thalamic-cerebellum circuitry in MDD with ED, providing preliminary insights into the neurobiology of abnormal eating behaviors in depression.

Yangyu Wu, Qilin Zhong, Jianzhao Zhang et al. · 0 citations

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