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Author

Guanghua Xiao

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Open access Oct 2026

SpatialOmicsLab: an integrated research environment for AI co-scientists in spatial transcriptomics

Spatial profiling is moving from method development into a central platform for biological discovery and clinical translation, but analyzing such complex data has become the bottleneck of scientific discovery. Translating spatial transcriptomic measurements into biological insight requires reproducible workflows that i...

Yi Jiang, Xiao-Wei Zhan, Pei-Ran Quan et al. · 0 citations
Open access Jul 2026

Spatial Topology Reveals Biologically Distinct Recurrent Motifs in Colorectal Cancer

STORM provides an annotation-free framework for discovering recurrent spatial motifs and identifies a fibroblast barrier architecture whose topological association with immune exclusion is independent of effector abundance, amplified in early-onset disease, and translatable to a deployable pathology-based prognostic bi...

Jia Yao, Yuqiu Yang, Yi Jiang et al. · 0 citations

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