Author

Guang-Hui Yu

3 papers indexed here

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Oct 2026

Rationally optimized split crRNA-based CRISPR/Cas12a platform for amplification-free miRNA detection.

MicroRNAs (miRNAs) are important biomarkers for cancer diagnosis and prognosis, but their short length, low abundance, and high sequence similarity make rapid and sensitive detection challenging. Split crRNA-based CRISPR/Cas12a systems have emerged as a promising amplification-free strategy for RNA detection, yet the d...

Shao-Zhen Cha, Peng Zhang, Jie Hou et al. · Biosensors & bioelectronics · 0 citations

Open access Sep 2026

Lineage tracing reveals KSP+ cells as multipotent progenitors driving postnatal renal development and injury repair via notch signaling

Background Progenitor cells generate multiple cells during development and are thought to be involved in tissue repair. The widespread distribution of Kidney-specific cadherin-positive (KSP+) cells in the kidney suggests they play an important role in renal development. However, direct evidence demonstrating that KSP+...

Xing-Hao Duan, Fu-Yue Ji, Hao-Yu Zhu et al. · Frontiers in Cell and Develo... · 0 citations

Open access Sep 2026

A Protocol for Accelerating Homozygous Line Screening in Arabidopsis thaliana

Obtaining homozygous mutant and transgenic lines is a critical yet time-consuming step in Arabidopsis thaliana research. Conventional breeding procedures require seeds to undergo complete maturation and natural desiccation before harvest, followed by cold stratification to overcome seed dormancy. This process substanti...

Qiu-Yu Zhang, Yi-Fan Wang, Cheng-Qi Jiang et al. · Bio-protocol · 0 citations