Guang-Kun Zhang

Gut-to-Liver Escape of Viable Streptococcus salivarius Fuels Alcoholic Liver Disease via Fn14-Dependent NF-κB Signaling

Gut microbial dysbiosis contributes to alcoholic liver disease (ALD), but the pathogenic bacteria and mechanisms remain unclear. We investigated the role of Streptococcus salivarius (S. salivarius) in ALD mice using a modified 12-week NIAAA chronic-plus-binge ethanol regimen with oral gavage. S. salivarius aggravated h...