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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Guang-Lin Liu

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Open access Sep 2026

Gut microbiota remodeling contributes to nicotine-associated behavioral improvement and restoration of serotonin-related metabolism in CUMS mice

Major depressive disorder is a heterogeneous neuropsychiatric disorder in which serotonin-related pathways remain important pharmacological targets. Nicotine has been reported to exert antidepressant-like effects, yet whether the gut microbiota contributes to these effects remains unclear. Here, we found that susta...

Xia Gao, Lei Fan, Guang-Lin Liu et al. · 0 citations
Open access Sep 2026

Adult-onset hippocampal α7 nicotinic acetylcholine receptor loss rapidly drives Alzheimer-like neuropathology in mice

Introduction The reduction of α7 nicotinic acetylcholine receptor (nAChR) in the hippocampus con-stitutes one of the neuropathological features observed in the brains of individuals with Alzheimer’s disease (AD), and α7 nAChR is crucial to cognitive process. However, studies involving α7 nAChR knockout mice have not de...

Jun Li, Guang-Lin Liu, Xiao-Tong Wang et al. · 0 citations

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