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Guang-Ning Liu

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Open access Aug 2026

A self-iterative orthogonal base-editing platform enables multiplex N-to-N diversification and genome-scale functional screening in Escherichia coli

MUTATOR is reported, a MUlTiplexAble and self-iTerative ORthogonal base-editing platform that enables N-to-N diversification in Escherichia coli and is established as a broadly applicable platform for genome-wide diversification, functional dissection, and rapid engineering of industrial microbial chassis.

Xiangrui Fan, Li-Ya Liang, Hongle Wang et al. · Nucleic Acids Research · 0 citations

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