Open access
Aug 2026
USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease
It is demonstrated that impaired pexophagy drives peroxisomal dysfunction and tubular damage in DKD and a critical role of USP30 mediated regulation of pexophagy is revealed and suggested that USP30 may serve as an experimental intervention target to alleviate tubular injury in DKD.
Jia Li, Chaoyang Hua, Guang-Pu Li et al.
· Advancement of science · 0 citations