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Guang-Rong Liu

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Open access Oct 2026

Hypofractionated Versus Conventionally Fractionated Postmastectomy Radiotherapy With Internal Mammary Node Irradiation for High-Risk Breast Cancer (HypoMast-IMNI): A Randomized Phase III Trial.

For patients with high-risk, operable breast cancer requiring PMRT with IMNI, the 16-fraction HypoRT regimen is noninferior to ConvRT for locoregional control, offers a superior acute toxicity profile, and demonstrates excellent cardiopulmonary safety.

Xiao-Fang Wang, Xiao-Meng Zhang, Xing-Xing Chen et al. · 0 citations
Open access Oct 2026

VCP‐Regulated LMF2 Stabilizes the Cholesterol Biosynthesis Enzyme HMGCS1 to Drive Cancer Progression and Confer Capecitabine Resistance in Triple‐Negative Breast Cancer

A previously unrecognized VCP‐LMF2‐HMGCS1 regulatory axis that drives TNBC progression and chemoresistance is unveiled, and lipase maturation factor 2 is identified as a promising therapeutic target for this recalcitrant disease.

Qian Zhao, Lisa Andriani, Yin-Ling Zhang et al. · 0 citations

Influence of a family history of breast and/or ovarian cancer on breast cancer outcomes

The results found that women diagnosed with FBC had an early onset of disease in the population studied, and the poor outcome of patients with a family history of BOC associated with survival was restricted to the hormone receptor-positive population.

A. Cao, Min He, G. Di et al. · 0 citations

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