Open access
Sep 2026
IL-11 drives Treg cell differentiation by activating the MBD3/APOH-mediated fatty acid oxidation axis to promote hepatocellular carcinoma.
BACKGROUND The immunosuppressive tumor microenvironment (TME) represents a major barrier to effective hepatocellular carcinoma (HCC) therapy. While interleukin-11 (IL-11) has been implicated in cancer progression, its immunomodulatory functions and underlying mechanisms in HCC remain poorly understood. METHODS We eva...
Yang Gao, Xi-Juan Yao, Xing Huang et al.
· Chinese Medical Journal · 0 citations