Lung cancer is one of the most prevalent and lethal malignancies worldwide, and radiotherapy serves as a standard therapeutic modality for the management of advanced or inoperable non-small cell lung cancer. However, radioresistance remains a major obstacle that compromises therapeutic efficacy and drives tumor recurre...
Shi-Fang Sang, Guang-Chao Lv, Shi-Yun Feng et al.· Frontiers in Cell and Develo...· 0 citations
Immune checkpoint blockade targeting the PD-1/PD-L1 axis has improved the treatment of non-small cell lung cancer (NSCLC), yet its therapeutic efficacy remains limited by insufficient antitumor immune activation. Herein, we developed a biomimetic manganese-amplified STING nanoagonist to potentiate PD-L1 blockade immuno...
Ye Guo, Shi-Yun Feng, Kai-Zhong Wang et al.· Colloids and Surfaces B: Bio...· 0 citations
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