Aug 2026
Adenosine 2A receptor drives microglial efferocytosis to accelerate white matter repair and functional recovery after stroke.
It is demonstrated that microglial adenosine 2A receptor (A2AR) is essential for spontaneous white matter regeneration after ischemic injury in mice and identified A2AR as a critical regulator of microglia-mediated white matter repair and a promising therapeutic target for enhancing regeneration after stroke.
Yanfang Deng, Qian He, Bolin Yao et al.
· Science Signaling · 0 citations