Open access
Aug 2026
Viral gene replication enhances AAV vector quality and reduces manufacturing costs.
AAV vector production with robust plasmid DNA in cellulo replication (AAVPCR) proves effective across serotypes and transgenes, offering broad potential to improve the safety, efficacy, and affordability of AAV gene therapies.
Hao Liu, Ailing Du, Nan Liu et al.
· Molecular Therapy · 0 citations