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Guangwen Liu

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Review Open access Jul 2026

Optimizing exercise modalities to enhance brain-derived neurotrophic factor levels in older adults: a Bayesian network and dose-response meta-analysis

Background Global aging leads to increased age-related cognitive decline and neurodegenerative diseases like dementia. Brain-derived neurotrophic factor (BDNF) is crucial for neuronal survival, synaptic plasticity, and cognitive function, but its levels often decline with age. Physical exercise can potentially elevate...

Guangwen Liu, Zhide Liang, Wance Wang et al. · 1 citation

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