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Author

Guijie Guo

2 papers indexed here

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Open access Sep 2026

PRRSV Nsp9 hijacks BNIP3-mediated autophagy to provide membrane platforms for viral replication complexes

ABSTRACT Porcine reproductive and respiratory syndrome virus (PRRSV) is a major pathogen threatening the global swine industry. The viral nonstructural protein 9 (Nsp9) harbors RNA-dependent RNA polymerase activity and acts as a core component of the viral replication complex, yet its interplay with host factors remain...

He-You Yi, Shao-Jun Wang, Gui-Jie Guo · 0 citations
Review Open access Aug 2026

Viral manipulation of DNA damage response signaling: molecular mechanisms and therapeutic implications.

The DNA damage response (DDR) network maintains genomic integrity, functions as a signaling hub that viruses exploit to drive pathogenesis, and constitutes a central interface between viral infection and host cell fate. This review discusses the molecular mechanisms by which viruses subvert host DDR pathways, with an e...

Mingyue Song, Shu-Yi Wang, Xiao Fei et al. · 0 citations

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