Pathogenicity and Genomic Analysis of Hypervirulent Aeromonas hydrophila NN0116 From Nile Tilapia and Head Kidney Transcriptome of Infected Fish Reveals a B-Cell-Dominated Immune Response.
Aeromonas hydrophila is a major pathogen of Motile Aeromonad Septicemia (MAS) in Nile tilapia, with pathogenesis and immunity poorly understood. In early 2026, a > 70% mortality outbreak occurred at a Nanning tilapia farm. The dominant strain NN0116 was identified as A. hydrophila by 16S rRNA and whole-genome ANI analy...