Review
Open access
Aug 2026
RNF213 in Panvascular Disease: A Molecular Hub Linking Genetic Susceptibility to Systemic Vasculopathy
This review synthesizes current evidence elucidating RNF213′s multifaceted roles in vascular homeostasis, spanning its functions as an E3 ubiquitin ligase, mechanosensor, and immune modulator and outlines unresolved questions regarding context-dependent effects of RNF213 variants and organ-specific regulatory mechanism...
Zhenghaonan Qiu, Guicheng Kuang, H. Ji et al.
· Biomedicines · 0 citations