Dual-Signal Amplification: Synergistic Integration of Nanozyme-Catalyzed SERS Aptasensor with μHPLC Pre-enrichment for Ultrasensitive ATP Monitoring.
The precise quantification of adenosine triphosphate (ATP) at physiologically critical femtomolar levels in complex biological fluids remains a formidable challenge, constrained by irreconcilable demands for extreme sensitivity, specificity, and operational robustness. Conventional integrated platforms, such as LC-SERS...