Guilherme Alexandre Soares Cargnin

Sex-related differences in clinical severity and neuroimaging burden in CADASIL: a systematic review

Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic cause of cerebral small vessel disease, resulting from mutations in the NOTCH3 gene and characterized by recurrent ischemic events, cognitive impairment, and a high burden of MRI...