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Author

G. Obozinski

2 papers indexed here

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Open access Oct 2026

Computational deconvolution of drug sensitivity via single-cell–to–bulk transcriptome mapping

Analyses routinely conducted in both fundamental research and biomedical studies often report aggregate signals derived from heterogeneous mixtures of cells. These mixtures reflect the intrinsic anatomical and functional complexity of the tissues and organs from which they are derived. Such bulk measurements obscure ce...

A. Coudray, Romain Forey, Benjamin Bejar Haro et al. · 0 citations
Preprint Aug 2026

A Structural FHMM for Interpretable Disease Trajectories in T2DM

The model identifies multiple clinically coherent latent components corresponding to known patterns of diabetes-related complications and reveals heterogeneous progression pathways, including distinct microvascular-dominant and multi-organ trajectories associated with elevated comorbidity burden and mortality.

Alessandro Mari, E. Krymova, Guillaume Obozinski et al. · 0 citations

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