Reshaping the definition of high-risk disease in the immune effector therapy era in multiple myeloma
Multiple myeloma (MM) outcomes have improved with proteasome inhibitors, immunomodulatory drugs, anti-CD38 antibodies, and transplantation, yet a subset of patients with high-risk MM (HRMM) continues to relapse early and die prematurely. Immune effector therapies (IET)—B-cell maturation antigen (BCMA)- and G protein–co...