Author

Guo-Hua Jiang

2 papers indexed here

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Open access Aug 2026

Hypertrophic cardiomyocytes promote cardiac fibrosis through paracrine secretion of ketoisoleucine in pressure-overloaded hearts

Cardiac fibrosis is a critical pathological feature that drives pressure overload (PO)-induced heart failure (HF). This process involves a complex intercellular crosstalk between cardiac fibroblasts (CFs) and cardiomyocytes. Cardiomyocyte hypertrophy is a compensatory response to PO and undergoes metabolic reprogra...

Chao-Fan Li, Guo-Hua Jiang, Tao Zhou et al. · Cell Death & Disease · 0 citations

Review Open access Sep 2026

Childhood adversity and disadvantage in relation to incident disability and multimorbidity: prospective analyses of ELSA and two SHARE inception samples

Childhood health adversity and socioeconomic disadvantage may shape late-life health, but evidence for incident disability and multimorbidity remains limited. Cross-cohort inference is complicated by non-equivalent measures of childhood experiences and differences in timing. We estimated cohort-specific prospective...

Tao Zhou, Guo-Hua Jiang, Ruijinlin Hao et al. · Frontiers in Public Health · 0 citations