Silk Fibroin/Polycaprolactone Coaxial Nanofibrous Scaffold Loaded with Kaempferol and Icariin: A Bioactive Macromolecular Platform for Bone Regeneration through Enhanced Antibacterial Activity and Osteoimmunomodulation.
This study aims to fabricate a scaffold based on natural herbal active substances, achieving antibacterial, anti-inflammatory, and osteogenic activities by graded and sustained drug release, overcoming the high cost and instability of growth factors in conventional bone defect scaffolds. Coaxial electrospinning was emp...