Open access
Aug 2026
Photoreceptor-derived FGF2 mediates a protective stress response without driving pathological retinal neovascularization in ischemic retinopathy
Fibroblast growth factor 2 (FGF2) is frequently induced during ischemic retinal injury and has traditionally been considered a pro-angiogenic factor based largely on studies using exogenous FGF2 administration. However, its endogenous cellular origin and physiological role remain incompletely understood. Here, we used...
Zhifei Wu, Lulu Peng, Jie-Chun Wu et al.
· bioRxiv · 0 citations