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Author

G. Chen

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Review Open access Nov 2026

Complex cases, endoscopic interventions, personalized techniques, and risk control: a bibliometric review of minimally invasive gallbladder surgery

Gallstones are a growing global public health issue linked to obesity and metabolic syndrome, and they impose substantial healthcare burdens through complications such as cholecystitis. Minimally invasive surgery is now widely used, but technical optimization and careful risk assessment remain important clinical ch...

Zu-Yuan Chen, Guo-Qiang Chen, Bei-Bei Huang et al. · 0 citations
Review Open access Sep 2026

Association Between Sleep Disorders and Breast Cancer: An Analysis Based on NHANES and Mendelian Randomization

Cross-sectional analysis of NHANES 2007–2018 cross-sectional data found no overall association between sleep disorders and BC, and Mendelian randomization provided suggestive evidence of a modest association between genetically predicted sleep disorders and ER−, but not ER+, BC.

Si-Yan Chen, Jian-Di Li, Ke-Jun Wu et al. · 0 citations
Open access Aug 2026

CRISPR Screen Reveals Pathways and Factors Driving Tyrosine Kinase Inhibitor Resistance in Hepatocellular Carcinoma

This study identified GPATCH4, CCT3, C19orf53, UACA, PPM1M, and LIN37 as key genes mediating TKI resistance in HCC, and identified Ferroptosis, epithelial‐mesenchymal transition and hypoxia were new research directions, which were closely related to the pathways investigated in this study.

Siyi Chen, Li-Hua Yang, Zi-Qian Liang et al. · 0 citations
Open access Jul 2026

A comprehensive study based on large-sample multi-omics integration and machine learning to decode mitochondria-associated genes: from digestive tract tumours to gastric cancer

New insights are provided into the differential expression and pathogenesis of LACTB2 in digestive tract tumours, particularly its prognostic and diagnostic value in GC.

Wei Zhang, Yushan Tang, Yi-Yang Chen et al. · 0 citations

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