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Guo-Yan Feng

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Open access Sep 2026

Depression and Longitudinal Frailty Trajectories in Middle-Aged and Older Adults with Chronic Pain: A 8-Year National Cohort Study in China

Background Global population aging is accelerating, and pain and depression frequently co-occur in middle-aged and older adults. Frailty, an age-related clinical syndrome, markedly elevates the risks of falls, disability, hospitalization, and mortality. This study investigated whether comorbid depression affects long-t...

Hao-Tian Zhang, Ai-Qi Wang, Shun Wang et al. · 0 citations

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