Guo-Zhen Chen

A Fluorescent Aptamer Sensor Based on Cu-TCPP/rGO for Homogeneous Screening of G-Quadruplex Ligands

Single-stranded human telomeric DNA can fold into G-quadruplexes, structures composed of stacked G-quartets. Ligands that target G-quadruplex DNA have received considerable attention because of their potential anticancer activity. We developed a Förster resonance energy transfer (FRET) system to identify drugs that...