JUND-DNAJB1-p21 axis drives fibroblast senescence to recruit CD4⁺ T cells in salivary gland pathogenesis of Sjögren’s disease
Advanced age is a recognized risk factor for primary Sjögren’s disease (pSjD), suggesting a role for aging-related mechanisms in its pathogenesis. However, whether cellular senescence directly drives autoimmune inflammation and glandular dysfunction remains unclear. Furthermore, the specific role of senescent fib...