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Author

Gurler Akpinar

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Open access Aug 2026

Biphasic Temporal Remodeling Of The Proteome In A Polyglutamine-Expanded Huntingtin In Vitro Aggregation Cell Model: From Early Rna-Regulatory Compensation To Selective Mitochondrial Energy Failure

Findings define a biphasic course of huntingtin toxicity and highlight an early therapeutic window in which intervention is most likely to be applied, prior to irreversible deterioration of mitochondrial respiratory function.

Ekin Sonmez, Pınar Mutlu, Cinla Ozlevent et al. · 0 citations

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