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Open access Sep 2026

Integrated Omics-Driven Discovery Reveals Synphilin-1-mediated Anoikis Resistance through p53 Downregulation.

Synphilin-1 is a protein that interacts with α-synuclein and has been implicated in Parkinson's disease. However, the cellular and molecular mechanisms underlying the effect of synphilin-1 in Parkinson's disease remain poorly understood. This study aimed to elucidate the molecular function of synphilin-1 using integrat...

Seok Gi Kim, Ye Eun Sim, Abdurazak Aman Ketebo et al. · 0 citations
Review Aug 2026

Unraveling the Intricacies of G-Protein-Coupled Receptor Signaling in Cardiovascular Diseases: Novel Perspectives From Regulation to Therapeutic Targeting.

The contributions of class A, class B, and other GPCR families to cardiovascular physiology and pathology are discussed, emphasizing their relevance to the development of targeted interventions for hypertension, heart failure, arrhythmias, atherosclerosis, and related CVDs.

Shaherin Basith, Gwang Lee · 0 citations

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