Oct 2026
An integrated microfluidic platform for tunable-stringency competitive affinity selection of folate receptor alpha aptamers.
This study developed a new microfluidic device for competitive affinity selection of single-stranded DNA (ssDNA) aptamers targeting folate receptor alpha (FRα), an ovarian cancer (OvCa) biomarker. The device integrated micropumps, microvalves, and micromixers to automate four selection rounds in ∼2.5 h, while washing s...
Yi-Da Chung, Yi-Cheng Tsai, Keng-Fu Hsu et al.
· Lab on a Chip · 0 citations