Author

H. Assress

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Open access Oct 2026

Performance evaluation of polarity switching for plasma untargeted metabolomics using Orbitrap mass spectrometer.

Untargeted metabolomics often requires separate positive and negative ionization mode injections to maximize metabolome coverage, increasing analytical time, analysis cost, and complexity. Polarity switching (PSW) represents a promising alternative, yet its adoption in untargeted metabolomics remains limited, likely du...

H. Assress, Ahmad Mani-Varnosfaderani, Bashar Amer et al. · Analytical and Bioanalytical... · 0 citations

Open access Jul 2026

Lactiplantibacillus plantarum promotes intestinal goblet cell differentiation via indole-3-lactic acid-AHR signaling in pigs.

The swine intestinal microbiota dynamically remodels during development and supports gut homeostasis. However, whether stage-specific microbial shifts, are associated with epithelial development remains poorly understood. Here, longitudinal metagenomic profiling of the swine gut microbiome identified Lactiplantibacillu...

Ziyu Liu, Haiqin Wu, S. Howe et al. · npj Biofilms and Microbiomes · 0 citations

Open access Aug 2026

From known chemical space to unannotated metabolites: a cluster-guided retention-time driven framework for biologically informed annotation

A two-step analytical approach was developed to systematically prioritize and interpret unannotated metabolites using plasma LC–MS/MS data from pregnant women with obesity as a biologically relevant test dataset, providing a scalable framework for prioritizing dark matter metabolites in untargeted metabolomics.

Dipendra Bhandari, H. Paz, Keith Henderson et al. · Metabolomics · 0 citations