Sep 2026
IDH3 regulates citrate homeostasis to control metabolic fitness and venetoclax resistance of AML stem cells.
Aykut Demir, Maximilian Mönnig, Nesrine Aroua et al.
· Blood · 0 citations
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Open access
Aug 2026
Divergent roles of interleukin-12p40 and interleukin-18 in severe fibrosing chronic graft-versus-host-disease, immunity, and post-transplant outcomes.
Chronic graft-versus-host disease (cGvHD) is a major cause of late morbidity after allogeneic hematopoietic stem-cell transplantation (alloHSCT), particularly in severe fibrosing forms. Although IFNγ-related cytokines have been implicated in cGvHD, their contributions to disease progression, survival, relapse, and resp...
Salim Oulghazi, L. Alasfar, Mark E. Robinson et al.
· Haematologica · 0 citations
Open access
Aug 2026
Development of an investigational medicinal stem cell gene therapy product to attempt curing human immunodeficiency virus infection
For most people living with Human immunodeficiency virus (HIV), virus control and sufficient immune function can be achieved with polypharmacotherapy. A minority is intolerant to thereto, and drug-resistant mutants are emerging. Additionally, people living with HIV (PLWH) have significantly higher risk of cardiovascula...
Laura Weigand, S. Herkt, Maike Voges et al.
· Scientific Reports · 0 citations